Yes, some people might experience a sense of tingling, or heat or redness in the skin, or a sense of flushing when taking Qualia NAD+.
Qualia NAD+ contains 3 different NAD+ precursors: (1) nicotinamide riboside, (2) niacinamide, and (3) niacin (nicotinic acid). The first two, nicotinamide riboside and niacinamide, are typically described as being non-flushing. The niacin (nicotinic acid) form of vitamin B3 can cause flushing; however, this usually only occurs when it is supplemented in amounts of 30 mg or more. In studies, it has been very rare to experience a niacin flush with 30 mg of nicotinic acid, but about half of people experience flushing when taking 500 mg of nicotinic acid. We formulated Qualia NAD+ to have less than 30 mg of the nicotinic acid form to reduce the chances of flushing—a 2 capsule serving of Qualia NAD+ only contains 20 mg of the flushing type of vitamin B3. Because of this, we expect flushing to be a rare experience when taking Qualia NAD+. But individual differences (i.e., genetics, gut microbiome, etc.) may make some people more prone to experiencing a niacin flush when supplementing even low amounts of nicotinic acid (and possibly even the non-flushing forms of niacin). Niacin flushing can be felt anywhere along a continuum of being a mild tingling sensation to feeling very uncomfortable—it can be experienced as feeling a lot like an allergic reaction. While it can be uncomfortable, a niacin flush is considered to be harmless and temporary, usually taking less than 1-2 hours to go away on its own. A general rule of thumb is that flushing is most intense after the first time someone takes a supplement containing nicotinic acid, and typically diminishes over days or weeks with continued use. However, flushing from low amounts of nicotinic acid can also occur sporadically and unpredictably. In other words, it's possible to take a supplement many times and never flush, and then one day experience flushing unexpectedly.*
If you experience a niacin flush after taking Qualia NAD+, and wish to continue taking it while decreasing the chance of flushing, our recommendation is to take 1 capsule rather than 2, and to retry the 2 capsule amount after several days to a week. If you continue to experience significant niacin flushing, Qualia NAD+ may not be a good fit for your unique biochemistry, and you may want to discontinue it and request your money back.
**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
The FDA has determined that NMN (nicotinamide mononucleotide) is excluded from the definition of dietary supplement, which essentially means it is not allowed to be sold as an ingredient used in a dietary supplement. NMN is not in our product because Qualia NAD+ is a dietary supplement.
Qualia NAD+ does not contain any ingredients reported to interact negatively with alcohol.*
The best time to take Qualia NAD+ is near the start of your day. Circadian (i.e., body clock) research in animals suggests that NAD+ boosting compounds offer better support for metabolic health when taken at the beginning of the day.
Qualia NAD+ is a 2-capsule-per-day product that exclusively supports NAD pathways and helps bolster NAD levels. Qualia Mitochondria+ requires up to 8 capsules per day and provides support for NAD while offering broader support for mitochondrial function, autophagy, stress management, and cellular metabolism.
Qualia NAD+ is designed to work beneath the surface (it's a cellular health supplement), so its primary purpose is not to deliver results you'd feel.
NAD+ is a critical molecule found in every cell in your body: it’s involved in hundreds of metabolic processes. NAD+ is most well-known for being involved in turning the energy in food into cellular energy (it’s a key player in metabolism) and regulating cellular functions related to maintenance, repair, and stress.
It’s fine to take Qualia NAD+ without food, and it contains less than 1 calorie, so it is fine to take before eating your first food of the day.*
Qualia NAD+ is a daily supplement that is uniquely formulated to support the body's innate capacity to produce, utilize, recycle NAD+, and ultimately sustain healthy NAD+ levels. This is important because NAD+ levels gradually decline with age, and adequate levels of NAD+ are needed to support cellular energy production and to keep cells healthy.*