Qualia NAD+ can increase circulatory function. A very small number of people might experience heat or redness in the skin or a sense of flushing. The nicotinic acid (niacin) form of vitamin B3 can cause flushing when taken in amounts substantially more than the daily value (DV) amount. However, we have not had customers inform us of the other symptoms you shared. We recommend checking with your physician to see if you may have an allergic reaction to one of the many ingredients in our NAD+ formulation. We do see you've reached out to our customer support team, and they have taken care of your account.