Learn everything you need to know about how zombie cells contribute to aging and effective ways to eliminate them for healthier aging and well-being.
What follows is a transcript for a Collective Insights episode where Dr. Heather Sandison shared the latest research on lifestyle interventions proven to slow cognitive decline, shattering common misconceptions about Alzheimer's and providing key insights to keeping our brain sharp at any age.
What follows is a transcript from our podcast with Steven Kotler where he fearlessly challenges long-standing myths surrounding aging.
What follows is a transcript from a Collective Insights podcast episode with Dr. Nick Bitz and Dr. Greg Kelly where we discussed one of the biggest aging breakthroughs of our time, senolytics.
By taking advantage of these science-backed ways to promote autophagy, you can support your overall health and cognitive function.
Cellular senescence is a state of irreversible growth arrest that turns functional cells into zombie cells. These senescent cells occur in all types of tissues and organs and the skin is no exception.
Improve your health and extend your lifespan with Qualia Senolytic, a dietary supplement designed to promote the removal of senescent cells
During the development of Qualia Senolytic, Qualia put our newest healthy aging product to the test to find out how users would respond.
The Qualia science team extensively reviewed scientific research on more than 80 ingredients before deciding on what to include in Qualia Skin. In this blog post, we’ll share some of the reasons why we chose each ingredient, the role it plays, and why we selected the dose we use.
There is an organ that we often take for granted and whose importance should probably be more acknowledged: the skin.
This study aimed to assess whether Qualia Skin, by providing skin nourishment from within and supporting comprehensive skin health and healthy skin aging, would change participant satisfaction and self-ratings of aspects of the skin’s feel and appearance.
Understanding the main aspects of skin health, the major processes and pathways of healthy skin physiology, and the mechanisms of skin aging is essential to learning how to keep the skin healthy and youthful.
The best way to understand how to keep the skin healthy and youthful is by understanding what are the factors that impact skin health and aging, which is what we’ll explore in this article.
The skin is a special organ that combines the body’s major systems: circulatory, nervous, muscular, immune, endocrine. It is a barrier that protects us against the threats in our environment, but it is also a sensory organ that allows us to perceive the outside world. Read on to understand both the structure and function of the skin.
Immunometabolism is the crosstalk between metabolic and immunological processes. Mitochondria, the cellular structures that generate cell energy, are key elements in the crosstalk between metabolic and immune signaling pathways.
Oxidative phosphorylation (OXPHOS) is the major pathway of ATP production. ATP is the energy-rich molecule that powers cellular processes that require energy input. OXPHOS occurs in mitochondria and uses energy extracted in the metabolism of cellular fuels, particularly in glycolysis, fatty acid oxidation, and the citric acid cycle, to power the production of ATP.
We invited the biohacking pioneer, Dave Asprey, to talk about the science backed practices to age better and live longer. He shares with us his favorite biohacks to improve your gut bacteria, your heart rate variability, your mitochondrial function and more. There is not just 1 thing that causes aging, but 7 functions that contribute to the aging process.
There is so much advice on longevity and aging that it can be hard to sort through all of the information. In this podcast transcript we dive into the science-backed approaches for living a longer and healthier life. Valter Longo, Ph.D., has thirty years of experience in longevity and healthy eating, and is one of the world’s experts in the field.
In 1958, Jack Preiss and Philip Handler published a scientific paper describing how NAD+ was made from niacin in three steps.(1) This pathway was later named the Preiss-Handler pathway after the co-discoverers. It describes the enzyme steps needed to convert niacin into the NAD+ molecule.
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The salvage pathway is used to produce NAD+ from nicotinamide molecules. Whether the source of the nicotinamide is vitamin B3 (as niacinamide), newer nicotinamides (e.g., nicotinamide riboside [NR], nicotinamide mononucleotide [NMN]), or molecules in food that get broken down during digestion into nicotinamide, the salvage pathway turns them into NAD+ in our tissues.
Most organisms have several alternatives for producing the NAD+ molecule. In humans, there are three major NAD+ biosynthesis pathways: the De Novo Pathway, starting from the essential amino acid L-tryptophan; the Preiss-Handler pathway, using niacin (nicotinic acid); and the Salvage Pathway from niacinamide (nicotinamide). In this article, we’ll be covering the De Novo Pathway.
Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. In this article, we explore lifestyle habits that improve mitochondrial health and support healthy aging.
Any way we can boost mitochondria helps us to increase the longevity of our cells and support energy production. Here we explore temperature and light therapy to improve mitochondrial health and support healthy aging.
In this article we’ll be covering the “big picture” when it comes to NAD. We’ll be doing a deeper dive on specific topics we introduce in this article in subsequent articles in this series. As you go through this series of articles please keep in mind that, like other molecules in the body, NAD+ is a means to an end. We don’t care about NAD+ on its own; we care about it because of what it allows cells to do.
